Author
Centre National de la Recherche ScientifiqueORCID 0000-0002-6218-0460Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Emilia A. Zin, Mélissa Desrosiers, Tommaso Ocari…·Deniz Dalkara
The paper investigates why engineered AAV variants have lower titers and finds that DNAse digestion heat reduces their stability, leading to artificially low titers.
Juliette Pulman, Catherine Botto, Hugo Malki…·Deniz Dalkara
This study delivers Cas9 or base editor RNP complexes directly to retinal cells, achieving gene editing in photoreceptors and RPE, but with toxicity at high concentrations.
Katia Avila‐Gutierrez, Leila Slaoui, Rodrigo Alvear‐Perez…·Martine Cohen‐Salmon
Alice Gilbert, Xabier Elorza‐Vidal, Armelle Rancillac…·Martine Cohen‐Salmon
This study shows that MLC1 is essential for postnatal development of the gliovascular unit, leading to vascular and fluid clearance defects in a mouse model of megalencephalic leukoencephalopathy.