Author

Catherine Botto

Centre National de la Recherche ScientifiqueORCID 0000-0002-2164-3852Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Anne De CianiD· 1 shared Aziz El-AmraouiiD· 1 shared Bruno SaubaméaiD· 1 shared Camille Robert· 1 shared Céline PortaliD· 1 shared Charlotte IzabelleiD· 1 shared Deniz DalkaraiD· 1 shared Duohao ReniD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBioengineering

Anne De CianORCID

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1 paper

Recent·Most cited

BioengineeringMolecular Therapy — Nucleic AcidsPeer-reviewedSep 30, 2024

Direct delivery of Cas9 or base editor protein and guide RNA complex enables genome editing in the retina

Juliette Pulman, Catherine Botto, Hugo Malki…·Deniz Dalkara

This study delivers Cas9 or base editor RNP complexes directly to retinal cells, achieving gene editing in photoreceptors and RPE, but with toxicity at high concentrations.

12 citations

mouseCRISPR screen

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