Line Lauritsen

The paper uses dynamic mode decomposition to analyze live-cell imaging data and investigates KIF13B's role in ciliary transport, finding it does not affect IFT velocity or frequency in a deletion mutant.

This study uses dynamic mode decomposition to analyze Ca2+ signaling in human astrocytes, showing cholesterol affects Ca2+ dynamics by shifting activity toward oscillatory states or suppressing it.

This study shows that the orientation of cholesterol's hydroxyl group affects membrane dynamics and intracellular transport in human astrocytes.

This paper presents novel intrinsically fluorescent cholesterol analogs with improved photophysical properties for live-cell imaging of sterol transport.

This study evaluates modified Nile Red dyes for super-resolution imaging of membrane packing in cells, finding differences in membrane structure between healthy and NPC1 disease fibroblasts.

This paper shows that ergosterol mediates natamycin aggregation in yeast plasma membranes, which underlies its antifungal activity and can be enhanced by sphingolipid inhibitors.

This paper quantifies GPCR intrinsic activation at the plasma membrane, revealing spatial multimodality with most receptors showing negligible spontaneous activation.