Maria Szomek

This study shows host-derived lipids are essential for tick cell proliferation and flavivirus output, revealing their role in regulating cellular state and viral production.

This study uses live-cell imaging and lipidomics to track LDL-derived cholesteryl esters in cells, revealing their transport and metabolism kinetics.

This paper presents novel intrinsically fluorescent cholesterol analogs with improved photophysical properties for live-cell imaging of sterol transport.

This study investigates the lipid binding properties of the yeast NCR1/NPC2 system using crystal structures and binding assays, revealing its ability to bind multiple lipids beyond sterols.

This study evaluates modified Nile Red dyes for super-resolution imaging of membrane packing in cells, finding differences in membrane structure between healthy and NPC1 disease fibroblasts.

This paper shows that ergosterol mediates natamycin aggregation in yeast plasma membranes, which underlies its antifungal activity and can be enhanced by sphingolipid inhibitors.

The paper develops a deep learning method to quantify lipophagy in yeast using fluorescence and cryo-soft X-ray microscopy data.

This study uses fluorescence and X-ray microscopy to show NPC2 facilitates cholesterol export from endo-lysosomes, altering membrane trafficking and organelle structure.