Author

Fabian Schuler

Innsbruck Medical UniversityORCID 0000-0002-6407-2818Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Andreas VillungeriD· 2 shared Andrea E. TijhuisiD· 1 shared Claudia ManzliD· 1 shared Diana C.M. SpieringsiD· 1 shared Floris FoijeriD· 1 shared Georg Alexander HäckeriD· 1 shared Gerlinde KarboniD· 1 shared Manuel Haschka· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

Andreas VillungerORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintSep 8, 2023

Chronic deregulation of the spindle assembly checkpoint triggers myelosuppression and gastrointestinal atrophy

Gerlinde Karbon, Fabian Schuler, Manuel Haschka…·Andreas Villunger

The paper investigates the effects of chronic SAC activation in mice, finding it causes bone marrow aplasia and intestinal atrophy, with BIM playing a critical role in gastrointestinal cell death.

DOI 10.1101/2023.09.08.556836

mouseexperimental assay

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Developmental BiologyEMBO ReportsPeer-reviewedJun 17, 2019

Checkpoint kinase 1 is essential for fetal haematopoiesis and hematopoietic stem cell survival

Fabian Schuler, Sehar Afreen, Claudia Manzl…·Andreas Villunger

This study shows that CHK1 is essential for hematopoietic stem cell survival and fetal hematopoiesis, and that its inhibition causes severe DNA damage and prevents HSC expansion.

31 citations

mouseexperimental assay

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