Rishikesh U. Kulkarni

This study shows that microglia secrete Neuraminidase-3 via extracellular vesicles to prune neurons contact-independently, disrupting network connectivity and contributing to neuroinflammatory diseases.

Hierarch is a Python package that performs hypothesis tests and computes confidence intervals for hierarchical experimental designs using resampling methods, with fast computation via Numba.

The paper develops a voltage imaging platform to study how glycans affect neuronal connectivity and shows specific glycan ablations impact functional connectivity in mouse hippocampal neurons.