Author

Taylor N. Takla

University of MichiganORCID 0000-0002-6546-5752Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Andrew M. TidballiD· 3 shared J. Clayton Walker· 3 shared Jack M. ParentiD· 3 shared Jinghui LuoiD· 2 shared Roksolana Sudyk· 2 shared Gemma L. CarvilliD· 1 shared Geoffrey G. MurphyiD· 1 shared Jonathan Z. SextoniD· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersNeuroscience

Andrew M. TidballORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

NeurosciencebioRxivPreprintDec 13, 2023

Genome-wide CRISPRi Screen in Human iNeurons to Identify Novel Focal Cortical Dysplasia Genes

Andrew M. Tidball, Jinghui Luo, J. Clayton Walker…·Jack M. Parent

The paper uses a CRISPRi screen in human iNeurons to identify novel FCD genes that increase mTOR signaling, finding two genes mutated in FCD patient tissue.

1 citation

humanCRISPR screen

𝕏 PostBluesky

NeuroscienceCellsPeer-reviewedJun 23, 2023

A shared pathogenic mechanism for valproic acid and SHROOM3 knockout in a brain organoid model of neural tube defects

Taylor N. Takla, Jinghui Luo, Roksolana Sudyk…·Andrew M. Tidball

This study identifies a shared mechanism of increased lumen size due to reduced apical constriction in brain organoids caused by valproic acid and SHROOM3 knockout.

22 citationstop 3%

humanspatial transcriptomics

𝕏 PostBluesky

NeurosciencebioRxivPreprintFeb 28, 2022

Self-organizing Single-Rosette Brain Organoids from Human Pluripotent Stem Cells

Andrew M. Tidball, Wei Niu, Qianyi Ma…·Jack M. Parent

The paper describes a method to generate reproducible single-rosette brain organoids from human pluripotent stem cells and uses them to study structural phenotypes in neurodevelopmental disorders.

11 citations

humanscRNA-seq

𝕏 PostBluesky