Integrated phenotypic screening and chemical proteomics identifies ETF1 ligands that modulate viral translation and replication
Arthur S. Kim, Kevin Ma, Christopher J. Reinhardt…·Benjamin F. Cravatt
Author
University of Wisconsin–MadisonORCID 0000-0002-6560-9680Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
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Arthur S. Kim, Kevin Ma, Christopher J. Reinhardt…·Benjamin F. Cravatt
Mateus Vailant Thomazella, Xueer Qiu, Cássia Gisele Terrassani Silveira…·Adam L. Bailey
This study identifies mesenteric ischemia and bacterial translocation as key drivers of the severe intoxication phase of yellow fever in humans and animals.
Kylie Nennig, Satyapramod Srinivasa Murthy, Sara Maloney…·Adam L. Bailey
This paper creates a mouse model of pegivirus infection and investigates immune mechanisms of persistence and cross-species infection.
Andrew C. Hunt, James Brett Case, Young‐Jun Park…·David A. Baker
The paper designs and characterizes trivalent miniprotein binders that neutralize SARS-CoV-2 variants with low pM IC50 values and provide prophylactic and therapeutic protection in mice.