Michael B. Gilbert

This study expands the HIF-2α proteomic interactome using TurboID proximity labeling, identifying 329 novel interactors and linking some to poor patient survival in breast cancer.

This study uses multi-omics analyses to show that TBCK deficiency disrupts ribosomal function, RNA splicing, and miRNA networks in TBCK-/- cells, providing insights into the molecular mechanisms of the disorder.

The paper identifies neuropeptides that specify and reprogram division of labor in leafcutter ants, showing their role in behavior and transcriptomic changes.

The paper investigates H3K9me3 heterochromatin dynamics in pluripotent cells, revealing distinct decay rates and mechanisms that maintain pluripotency.

This study identifies NUCKS1 as a novel SIRT7 interactor that promotes chromatin binding during senescence and liver aging, leading to metabolic and inflammatory gene expression.

The paper identifies a SIRT6 variant enriched in centenarians that improves genome stability through enhanced mADPr activity and interaction with Lamin A.