ImmunologybioRxivPreprint
In vivo genome-wide CRISPR screens in human T cells to enhance T cell therapy for solid tumors
Qi Liu, Peixin Amy Chen, Esha Urs…·Julia C. Carnevale
This paper performs in vivo CRISPR screens in human T cells to identify genetic modifiers of T cell function in solid tumors, finding P2RY8-G13 and GNAS as key regulators.