Author

Haozhou Tan

Rutgers, The State University of New JerseyORCID 0000-0002-6640-8354Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:protein structure· 1

Frequent Co-Authors

Jun WangiD· 2 shared Ahmadullah AnsariiD· 1 shared Aiden C Jaskolka-BrowniD· 1 shared Alexandra Ford· 1 shared Aliaksandra Frazier· 1 shared Ashima ChopraiD· 1 shared Bin TaniD· 1 shared Eddy ArnoldiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMolecular Biology

Jun WangORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintApr 1, 2024

Distal Protein-Protein Interactions Contribute to SARS-CoV-2 Main Protease Substrate Binding and Nirmatrelvir Resistance

Eric M. Lewandowski, Xiujun Zhang, Haozhou Tan…·Yu Chen

This study shows that non-active site mutations in SARS-CoV-2 Mpro enhance dimer-dimer interactions, aiding substrate binding and resistance to nirmatrelvir.

2 citations

protein structureexperimental assay

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MicrobiologySciencePeer-reviewedMar 28, 2024

Design of SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model

Bin Tan, Xiaoming Zhang, Ahmadullah Ansari…·Jun Wang

The paper designs SARS-CoV-2 PLpro inhibitors that show antiviral efficacy in a mouse model against SARS-CoV-2 and its variants.

140 citationstop 1%

mouseexperimental assay

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