Author

Igor Bittencourt dos Santos

Universidade Federal do Rio de JaneiroORCID 0000-0002-6646-8592Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2

Frequent Co-Authors

Alessandra Marcia da Fonseca-MartinsiD· 2 shared Daniel Cláudio Oliveira GomesiD· 2 shared Herbert Leonel de Matos GuedesiD· 2 shared Tadeu Diniz RamosiD· 2 shared Alisson Amaral da RochaiD· 1 shared Beatriz Toja de MirandaiD· 1 shared Bruno Silva‐SantosiD· 1 shared Camila FernandeziD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

Alessandra Marcia da Fonseca-MartinsORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintFeb 3, 2026

Adipose-Derived Extracellular Vesicles Mitigate Experimental Cutaneous Leishmaniasis Through an IL-10 Dependent Mechanism

Douglas Barroso de Almeida, Camila Fernandez, Alisson Amaral da Rocha…·Herbert Leonel de Matos Guedes

This study shows that adipose-derived mesenchymal stem cell extracellular vesicles reduce cutaneous leishmaniasis severity through IL-10-dependent immunomodulation without affecting parasite load.

DOI 10.64898/2026.02.02.703256

mouseexperimental assay

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ImmunologyJournal of Leukocyte BiologyPeer-reviewedDec 3, 2024

IL-17A/IFN-γ producing γ δ T cell functional dichotomy impacts cutaneous leishmaniasis in mice

Júlio Souza dos-Santos, Luan Firmino-Cruz, Diogo Oliveira-Maciel…·Herbert Leonel de Matos Guedes

This study shows that IL-17A-producing γδ T cells drive pathogenesis while IFN-γ-producing γδ T cells have therapeutic potential in cutaneous leishmaniasis.

8 citations

mouseexperimental assay

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