Udayan M. Apte

The paper identifies co-expressed gene sets linked to molecular initiating events in rodent liver carcinogenesis by comparing wild-type and knockout rats exposed to chemical activators.

The paper uses multi-omics analysis to show OGT regulates aneuploidy by fine-tuning multiple cellular pathways through O-GlcNAcylation.

This study examines the role of HNF4-cMyc interaction in liver injury and regeneration using a CDE diet model, finding that HNF4 deletion increases injury while cMyc deletion decreases it, with combined deletion leading to a unique HPC activation phenotype.

This study identifies HNF4a's role in regulating acyl chain remodeling and ether lipid accumulation in hepatic steatosis through cold stress-induced changes in lipid metabolism.

This study shows that Thm1 deletion in juvenile Pkd2 mice worsens biliary development and PLD, while adult Thm1 deletion has no effect, highlighting distinct roles of IFT-A and IFT-B in liver disease.