Author

Stephen Bentley Wheatcroft

University of LeedsORCID 0000-0002-6741-9012Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Mark T. KearneyiD· 2 shared Angara Sureshbabu· 1 shared Chiahsuan Chin· 1 shared Chloe G. MyersiD· 1 shared Colin W. G. FishwickiD· 1 shared David J. BeechiD· 1 shared David J. Flint· 1 shared Eva M. ClavaneiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

Mark T. KearneyORCID

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2 papers

Recent·Most cited

Cell BiologyMolecular and Cellular EndocrinologyPeer-reviewedOct 16, 2024

Small molecule modulation of insulin receptor-insulin like growth factor-1 receptor heterodimers in human endothelial cells

Chloe G. Myers, Hema Viswambharan, Natalie J. Haywood…·Katie J. Simmons

This paper identifies a small molecule that reduces IR:IGF-1R hybrid formation in human endothelial cells, increasing Akt phosphorylation and altering PI3-kinase signaling.

1 citation

humanexperimental assay

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Molecular BiologybioRxivPreprintJan 21, 2021

IGFBP2 protects against pulmonary fibrosis through inhibiting P21-mediated senescence

Chiahsuan Chin, John Lee, Ranjith Ravichandran…·Angara Sureshbabu

This study shows that IGFBP2 inhibits senescence and pulmonary fibrosis by suppressing P21 in aged mice, with epigenetic downregulation of Igfbp2 contributing to fibrosis.

2 citations

mousebulk RNA-seq

𝕏 PostBluesky