Tharvesh M. Liyakat Ali

This study introduces a co-aggregation method to improve morphogenesis and lineage representation in human stem cell-based embryo models.

The paper describes a modular co-aggregation strategy to recreate embryonic-extraembryonic interactions in vitro, leading to more complex gastruloid morphotypes with improved lineage diversity and patterning.

The paper identifies TAD cliques as repressive chromatin domains with distinct structural and functional features across cell types.

The paper identifies a primate-specific retroviral enhancer that integrates the XACT lncRNA into the human pluripotency network through evolutionary adaptation.