Author
University of HelsinkiORCID 0000-0002-6759-8997Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Jie Bao, Sanna Pikkusaari, Jun Dai…·Jing Ping Tang
This study identifies BX-912 as a therapeutic agent for ovarian serous carcinoma, revealing HES1 as a target and showing synergistic effects with olaparib.
Ashwini Sakrepatna Nagaraj, Matilda Salko, Aditi Sirsikar…·Anniina Färkkilä
Elli-Mari Aska, Denis Đermadi, Liisa Kauppi
The paper uses single-cell exome sequencing to study how replication errors, H3K36me3, and MMR shape the mutational landscape in mouse thymocytes.
Kul S. Shrestha, Elli-Mari Aska, Minna M. Tuominen, Liisa Kauppi
This study shows that Mlh1 haploinsufficiency causes microsatellite instability specifically in the intestine, not in the spleen, before tumorigenesis.
Laurent Acquaviva, Michiel Boekhout, Mehmet E. Karasu…·Scott Keeney
The paper identifies cis- and trans-acting factors that drive meiotic DNA break formation in the mouse pseudoautosomal region, revealing structural and molecular mechanisms essential for recombination and segregation.
Chiara Facciotto, Julia Casado, Laura Turunen…·Sampsa Hautaniemi
This study identifies epigenetic inhibitors that enhance the effectiveness of immunochemotherapy in DLBCL by disrupting DNA repair and cell cycle pathways.