Sara Mahallati

Pynapple provides an open-source framework for analyzing time-resolved data in systems neuroscience, offering easy-to-use objects and methods for data manipulation and analysis.

The paper identifies age-related increases in sag voltage amplitude in human pyramidal neurons and shows reduced baseline firing in older neuron microcircuits.

CellExplorer provides a framework for visualizing and characterizing single neuron features through standardized processing and a graphical interface.

The paper evaluates methods for estimating cluster structure in neuronal spike data and introduces iVAT for visualization without dimensionality reduction, showing t-SNE provides more reliable clustering results.