Shuang Chen

This paper computationally designs a PAM-relaxed SaCas9 variant, KRH, with expanded targeting capability and enhanced editing efficiency.

This study shows that SIRT1 activation reduces vasculitis severity in a murine model of Kawasaki disease by enhancing autophagy and mitophagy.

The paper introduces SAAINT-parser, a tool for extracting antibody and antibody-antigen interaction data from PDB, resulting in SAAINT-DB, which offers more accurate and comprehensive data than existing databases.