Author

Ryuichi Ohgaki

Institute for Open and Transdisciplinary Research InitiativesORCID 0000-0002-6894-7239Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:protein structure prediction· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:structural biology· 1

Frequent Co-Authors

Chunhuan JiniD· 2 shared Keitaro YamashitaiD· 2 shared Osamu NurekiiD· 2 shared Yoshikatsu KanaiiD· 2 shared Garib N. MurshudoviD· 1 shared Kan KobayashiiD· 1 shared Lili QuaniD· 1 shared Minhui XuiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiochemistry

Chunhuan JinORCID

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2 papers

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedFeb 14, 2025

Structural basis of anticancer drug recognition and amino acid transport by LAT1

Yongchan Lee, Chunhuan Jin, Ryuichi Ohgaki…·Yoshikatsu Kanai

This study reports six LAT1 structures bound with ligands, revealing substrate recognition and inhibition mechanisms, including the role of JPH203 as an anticancer drug.

40 citationstop 1%

humanstructural biology

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Molecular BiologybioRxivPreprintNov 3, 2021

Structural insights into human excitatory amino acid transporter EAAT2

T. Kato, Tsukasa Kusakizako, Chunhuan Jin…·Osamu Nureki

This study reports cryo-EM structures of human EAAT2 in substrate-free and inhibitor-bound states, revealing structural features and the mechanism of selective inhibition.

2 citations

humanexperimental assay

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