Author

Xi Chen

Chinese Academy of SciencesORCID 0000-0002-6922-2838Unclaimed ORCID profile · follow to get notified of new preprints

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Xi Chen13 papers · AstraZeneca (United States)

Biology Disciplines

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Neuroscience· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Assay:electronic health records· 1 Approach:experimental assay· 1 Assay:imaging· 1 Approach:machine learning (classical)· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Hua HaniD· 3 shared Bei HongiD· 1 shared Bing LiiD· 1 shared Bohao CheniD· 1 shared Chang ShuiD· 1 shared Chao‐Yu YangiD· 1 shared Danqian LiuiD· 1 shared Fan JiaiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersNeuroscience

Hua HanORCID

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3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintAug 26, 2025

Volumetric Denoising: An Approach to Boost Acquisition and Downstream Analysis of Volume Electron Microscopy

Bohao Chen, Fangfang Wang, Haoyu Wang…·Yunfeng Hua

This paper develops a volumetric denoising approach to improve VEM acquisition speed and downstream analysis by optimizing resolution and noise handling.

DOI 10.1101/2025.08.26.672334

machine learning (classical)

𝕏 PostBluesky

NeuroscienceCell ReportsPeer-reviewedAug 1, 2022

Fear memory-associated synaptic and mitochondrial changes revealed by deep learning-based processing of electron microscopy data

Jing Liu, Junqian Qi, Xi Chen…·Yang Yang

The paper uses deep learning to analyze electron microscopy data from mouse auditory cortex, revealing structural changes in synapses and mitochondria associated with fear memory.

33 citations

mouseelectronic health records

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NeuroscienceNational Science ReviewPeer-reviewedApr 15, 2019

Scalable volumetric imaging for ultrahigh-speed brain mapping at synaptic resolution

Hao Wang, Qingyuan Zhu, Lufeng Ding…·Guo‐Qiang Bi

This paper introduces a light-sheet microscopy method for fast, large-scale volumetric brain imaging at synaptic resolution, achieving whole mouse brain scans in 2 hours.

78 citations

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