Tobias Bruegmann

This study shows that peroxisome dysfunction in mice and engineered human myocardium leads to heart failure through metabolic impairment and disrupted cellular respiration.

The paper introduces tools to selectively enhance Gi/o-mediated GIRK currents in excitable cells using light-activated GPCRs.

This paper demonstrates thermogenetics as an alternative to implantable devices for heart pacing by using TRPV1 activation with heat pulses.

This paper introduces ChReef, an improved optogenetic tool with enhanced performance in sensory and cardiac systems, demonstrating its effectiveness in restoring visual and auditory function.