Julien Orlans

The paper introduces a 3D-printed fixed-target platform for macromolecular crystallography that simplifies microcrystal handling and data collection at synchrotrons.

This paper introduces a polymer film technology for serial macromolecular crystallography that provides an efficient hydration barrier and low X-ray background.

This study presents room-temperature structures of PBP2a using SFX to reveal dynamic features and conformational changes relevant to antibiotic resistance.

This paper combines MicroED and native mass spectrometry to determine structures of enzyme-inhibitor complexes and identify high-affinity ligands from crude samples.

This paper demonstrates how the crystallophore TbXo4 accelerates protein crystallization, enabling high-quality crystals for serial crystallography methods.

This study determines the structure of hNQO1 with NADH using serial crystallography and simulations, showing NADH binding stabilizes the protein and drives functional cooperativity through structural communication.

This paper develops a droplet microfluidics approach to produce uniform crystals and enable rapid micromixing for time-resolved serial crystallography.