Author

Bruno Frederico

AstraZeneca (United Kingdom)ORCID 0000-0002-6985-3090Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Diane MauriceiD· 1 shared Francesco GualdriniiD· 1 shared Jessica DiringiD· 1 shared Patrick S. CostelloiD· 1 shared Richard TreismaniD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperImmunology

Diane MauriceORCID

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1 paper

Recent·Most cited

ImmunologyNature CommunicationsPeer-reviewedSep 11, 2024

Defective cytoskeletal dynamics underlies the essential role of MRTF-SRF in IL-2 delivery to CD8+ T cells during infectious challenge

Diane Maurice, Patrick S. Costello, Jessica Diring…·Richard Treisman

This study shows that MRTF-SRF is essential for CD8+ T cell expansion and memory persistence during infection by regulating cytoskeletal dynamics and IL-2 signaling.

5 citations

mousebulk RNA-seq

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