Janet Brownlees

The study shows MitoTracker transfers from astrocytes to neurons without requiring mitochondrial transfer.

The paper investigates AMBRA1 mutants to identify strategies that prevent apoptosis and enhance autophagy/mitophagy in neurodegeneration, finding that AMBRA1TAT, which disrupts DLC1 interaction, shows the most promise.

This study evaluates IL-34 inhibition as a strategy to reduce microglial proliferation in prion disease, showing tissue-selectivity and reduced side effects compared to CSF1R inhibition.