Yuchi Qiu

This paper introduces TopFit, a framework that combines persistent spectral theory and sequence embeddings to predict protein fitness from mutations, validated on 34 benchmark datasets.

The paper develops a stochastic multiscale cell-based model to study how multiple morphogens and tissue dynamics regulate segment formation in the zebrafish hindbrain.

The paper investigates how Dpp morphogen gradients scale in Drosophila wing discs and proposes an alternative feedback model to explain scaling failure in mutants.