Anna K. Coussens

The paper identifies a regulatory mechanism in Mycobacterium tuberculosis that controls metabolic flux through coordinated enzyme abundance and metabolite effects, likened to a mixer tap.

The paper uses ddPCR to detect and quantify Mtb and HIV-1 in spinal tuberculosis biopsies, finding reciprocal relationships between pathogen abundance and immune microenvironment factors.

This study shows that T-type calcium channel blockers reduce SARS-CoV-2 spread via apoptotic bodies and limit cytokine storms in macrophages.

This study shows HIV-1 evades apoptosis in macrophages by manipulating the MAP2K1/ERK2 pathway to dysregulate lincRNA-p21, and suggests MAP2K1/ERK2 inhibitors as a therapeutic strategy.