Christopher K. Barlow

This paper generates a novel Slc7a9G105R mouse model to study cystinuria, identifying new biomarkers and therapeutic insights.

This study identifies quinone-transporting filaments in Bacillus subtilis as an alternative to membrane invaginations for expanding respiratory capacity in Gram-positive bacteria.

The paper identifies a regulatory mechanism in Mycobacterium tuberculosis that controls metabolic flux through coordinated enzyme abundance and metabolite effects, likened to a mixer tap.

This study shows that microbial assimilation of DMS and DMSO can occur through non-enzymatic oxidative mechanisms driven by light and heat, producing methanesulfonic acid and sulfite.

This study maps metabolic diversity in Klebsiella pneumoniae sub-lineages using genomics and metabolic modeling, revealing lineage-specific metabolic profiles that support coexistence through cross-feeding.

This study identifies how Mo-CODH and CoxG in Mycobacterium smegmatis oxidize CO and transfer electrons to the respiratory chain via quinone transport.

This study establishes a Drosophila model of ECHS1 deficiency and shows that valine restriction improves larval survival.

This paper introduces an adjusted diet formula for Drosophila melanogaster larvae to improve growth, development, and survival, with applications in studying metabolic disorders.

This study shows sodium selenate reduces seizures, cognitive dysfunction, and sensorimotor deficits in a rat model of chronic drug-resistant temporal lobe epilepsy.