Daniel A. Kramer

This study shows that the CCC complex regulates PI(3)P levels on phagosomal membranes, which is critical for phagosome maturation and antibacterial immunity.

This study identifies TgWIP interactions with Nck1/Grb2 and the WAVE complex to reveal how Toxoplasma manipulates host cell actin dynamics and motility.

This study identifies the Rab32-LRMDA-Retriever complex as essential for endolysosomal trafficking in innate immune cells, maintaining intestinal immune homeostasis.

This study determines the structure of the Retriever-SNX17 complex using cryo-EM, revealing how SNX17 interacts with Retriever to facilitate endosomal sorting of cargo proteins.

This study demonstrates light-controlled actin polymerization in protocells, enabling directed motility and revealing the role of branched and linear actin networks in membrane protrusion.

This paper identifies a DCC variant causing mirror movement disorder and shows it disrupts the DCC-WAVE regulatory complex interaction, essential for Netrin-1 signaling.