Swayam Prakash Srivastava

This study shows that AMPK is not essential for normal podocyte function but is critical for preventing glomerular fibrosis in diabetes.

This study shows HUWE1 enhances mTORC1 activity by promoting Rheb interaction with mTORC1 and supports de novo pyrimidine synthesis via CAD activation.

This study shows that endothelial ANGPTL4 depletion prevents diabetic kidney disease by improving metabolic function and reducing inflammation.

This study identifies Angptl4 as a fibrogenic molecule in diabetic kidney disease and shows that targeting its expression in kidneys reduces fibrosis and proteinuria.