Thomas Joshua Meyer

This study shows that c-Myc protein stability determines the response of Ras-mutant multiple myeloma cells to RAS and MEK inhibitors, suggesting direct RAS targeting is more effective.

The paper develops a high-throughput assay to test retrotransposon jumping activity and identifies variants that influence transposition.

This study shows that tRNA acetylation regulates stress signaling in mammals by affecting ribosome function and interacting with the Gcn2 kinase.

This paper develops a 3D self-assembly system to engineer tumor stroma-like structures using decellularized ECM and cancer cells, showing effects on malignancy and metabolism.

This study identifies lnc-FANCI-2 as a regulator of RAS signaling in HPV16-infected cervical cancer, showing its role in lesion progression and patient survival.

The paper identifies MPC1 as a key driver of PARP inhibitor resistance in NSCLC lung cancer through a metabolism-focused CRISPR screen.

This study examines how chromosomal rearrangements in the gibbon genome affect TAD boundaries and epigenetic features, finding overlap between rearrangement breakpoints and TAD boundaries.