Melanie Greter

The paper identifies a fibroblast-IL-7 feedback loop that promotes immunosuppressive monocyte-derived cells, which restrain CD4+ T cell responses during infection.

This study identifies reprogrammed neutrophils with impaired transit mechanics as a driver of multi-organ capillary stalling after stroke, showing therapeutic potential through Fgr inhibition.

The paper identifies a novel macrophage-like population in exocrine glands sustained by ILC2-derived GM-CSF, showing conservation across species.

This study identifies a proliferative-to-quiescent switch in microglial development and links it to epigenetic regulation and phagocytic function.

This study identifies TGF-β as a key mediator of macrophage specialization in the skin through interaction with sensory nerves.

This study shows that c-Myc inhibition enhances macrophage antimycobacterial activity and reduces MTB persistence in both in vitro and in vivo models.

This study identifies meningeal monocyte-derived macrophages as drivers of progressive multiple sclerosis using single-cell and spatial transcriptomics.

This study identifies GM-CSF-producing helper T cells as drivers of immunopathology, showing Treg cells restrain them to prevent tissue damage in mice.

This study identifies early yolk sac-derived macrophages in the pituitary gland and shows their role in hormonal regulation and post-pubertal gene expression.

This study shows that pericytes restrict immune cell entry into the CNS by maintaining immune quiescence of brain endothelial cells, and their deficiency leads to increased leukocyte infiltration and severe neuroinflammation.

This study shows microglia control vessel calcification via TREM2, with ablation worsening calcification and revealing a new role in preventing ectopic calcification.