Serge Mostowy

The paper identifies UFMylation as an antibacterial pathway using proximity biotinylation and mass spectrometry, showing it targets intracellular Shigella and Salmonella.

This study shows that septins are required for haematopoiesis in zebrafish, as septin-deficient larvae have increased HSPCs and myeloid bias, with implications for blood disorders.

This study identifies MenG inhibitors that restore bedaquiline susceptibility in resistant tuberculosis strains through menaquinone pathway disruption.

This study identifies enhanced virulence and stress tolerance as factors contributing to the epidemiological success of Shigella sonnei, using zebrafish models and genomic analysis.

This study shows that telomerase reverse transcriptase (Tert) is essential for resistance to mycobacterial infection by supporting demand-driven hematopoiesis in zebrafish.

The paper provides 15 genomically characterized Shigella sonnei isolates representing diverse sub-clades, with complete genome sequences and public availability for research.

The paper uses high-resolution microscopy and deep learning to analyze host and bacterial heterogeneity during Shigella infection, revealing SEPT7 recruitment patterns linked to T3SS activation.

This paper introduces a mimicry embedding strategy to enable efficient deep learning for 3D biomedical micrographs by mimicking verified datasets.