Author

Rajani Kanth Gudipati

Adam Mickiewicz University in PoznańORCID 0000-0002-7364-9279Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 3 Approach:experimental assay· 3 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Daniel HeßiD· 3 shared Helge GroßhansiD· 3 shared Charlotte SonesoniD· 2 shared Jan SeebacheriD· 2 shared Afzal AmanullahiD· 1 shared Ankit RoyiD· 1 shared Dimos GaidatzisiD· 1 shared Foivos GypasiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersMolecular Biology

Daniel HeßORCID

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3 papers

Recent·Most cited

Molecular BiologyEMBO ReportsPeer-reviewedJun 19, 2026

Cleavage of MEP-1 by DPF-3 Reveals Novel Substrate Specificity and Its Impact on Reproductive Fitness

Ilkin Aygun, Afzal Amanullah, Jan Seebacher…·Rajani Kanth Gudipati

The paper identifies MEP-1 as a novel substrate of DPF-3, showing cleavage after threonine and demonstrating its impact on reproductive fitness.

1 citation

C. elegansproteomics

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BiochemistryMolecular Systems BiologyPeer-reviewedOct 28, 2024

Massively parallel quantification of substrate turnover defines protease subsite cooperativity

Rajani Kanth Gudipati, Dimos Gaidatzis, Jan Seebacher…·Helge Großhans

The paper develops qPISA to quantify protease substrate turnover, revealing subsite cooperativity in DPP4 and distinguishing it from DPF-3.

7 citations

humanC. elegans

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Molecular BiologyMolecular CellPeer-reviewedApr 15, 2021

Protease-mediated processing of Argonaute proteins controls small RNA association

Rajani Kanth Gudipati, Kathrin Braun, Foivos Gypas…·Helge Großhans

The paper shows that proteolytic processing of Argonaute proteins by DPF-3 regulates small RNA association, maintaining genome integrity and fertility in C. elegans.

27 citations

C. elegansexperimental assay

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