Author

Yongjuan Guan

University of PennsylvaniaORCID 0000-0001-8981-0736Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Developmental Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

P. Jeremy WangiD· 3 shared Nicolae Adrian Leu· 2 shared Anastassios VourekasiD· 1 shared Devanshi JainiD· 1 shared Guanxiang LiangiD· 1 shared Hongyan GaoiD· 1 shared Huijuan Lin· 1 shared Isabella G. Cossu· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersDevelopmental Biology

P. Jeremy WangORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cell BiologyeLifePeer-reviewedNov 22, 2023

TRIP13 localizes to synapsed chromosomes and functions as a dosage-sensitive regulator of meiosis

Jessica Y. Chotiner, Nicolae Adrian Leu, Yang Fang…·P. Jeremy Wang

This study shows TRIP13 localizes to synapsed chromosomes and is a dosage-sensitive regulator of meiosis, with loss leading to sterility and meiotic defects.

22 citations

mouseproteomics

𝕏 PostBluesky

Developmental BiologyPLoS GeneticsPeer-reviewedMay 1, 2023

The MOV10 RNA helicase is a dosage-dependent host restriction factor for LINE1 retrotransposition in mice

Yongjuan Guan, Hongyan Gao, Nicolae Adrian Leu…·P. Jeremy Wang

This study shows MOV10 restricts LINE1 retrotransposition in mice in a dosage-dependent manner, affecting reproductive fitness and transcriptome regulation.

8 citations

mouseexperimental assay

𝕏 PostBluesky

Developmental BiologyPLoS GeneticsPeer-reviewedFeb 26, 2021

yama , a mutant allele of Mov10l1, disrupts retrotransposon silencing and piRNA biogenesis

Yongjuan Guan, Devanshi Jain, Scott Keeney, P. Jeremy Wang

The paper identifies a mutation in Mov10l1 that disrupts piRNA biogenesis and causes male sterility by affecting retrotransposon silencing.

15 citations

mouseexperimental assay

𝕏 PostBluesky