Steven G. Sayson

This paper develops a method to genetically modify Pneumocystis murina using extracellular vesicles for CRISPR/Cas9 delivery, achieving stable in vivo gene editing and transgene expression.

This study uses scRNA-seq to map the life cycle of Pneumocystis carinii, identifying transcriptional states associated with developmental stages and reproductive transitions.

This study identifies NLRP3 inflammasome activation and NETosis in P. murina pneumonia, highlighting neutrophils' role in inflammation and tissue damage.