Steven R. Caliari

This study develops collagen-glycosaminoglycan scaffolds with aligned pores and basement membrane proteins to enhance skeletal muscle tissue engineering.

This study shows that hydrogel stiffness and viscoelasticity influence fibroblast senescence, with viscoelasticity uniquely promoting senescence even without genotoxic stress.

This paper develops a multicompartment collagen scaffold with aligned pores and conductive regions to mimic the muscle-tendon junction, supporting stratified cell behavior and maintaining mechanical properties.

The paper develops an agent-based model to show how senescent cell behavior and tissue mechanics contribute to pulmonary fibrosis in aged mice.

This study shows fibrous granular scaffolds with directional persistence guide myotube organization better than isotropic scaffolds.

The paper examines lung viscoelasticity in bleomycin-induced fibrosis in mice, finding preserved viscoelastic properties despite increased stiffness.

This study shows heparin-modified collagen-GAG scaffolds enhance myoblast metabolic activity and myogenic differentiation compared to other GAG scaffolds.

This study identifies CDH11 as a mediator of fibroblast activation by integrating mechanical and inflammatory signals in pulmonary fibrosis.

This study shows that norbornene homopolymerization limits cell spreading in thiol-ene hydrogels, and reducing norbornene density improves hydrogel relaxation and cell morphology.

This paper develops a FUS-responsive granular hydrogel system that stabilizes through crosslinking and porosity control, showing potential for minimally invasive tissue regeneration.

This study shows that direct M2 macrophage co-culture promotes fibroblast activation regardless of hydrogel stiffness, mediated by IL6 signaling.

This study evaluates the effectiveness of collagen-glycosaminoglycan scaffolds in repairing volumetric muscle loss injuries in rats, showing improved muscle function and cellular repair.

This paper introduces a modular hydrogel platform for high-throughput cell culture applications, enabling efficient fabrication and characterization of viscoelastic hydrogels with reduced material and time usage.