Wendy González

The paper identifies five ion channel architectures essential for prokaryotic viability, with mechanosensitive channels being the most abundant.

This study identifies a KCNC1 variant linked to Rett syndrome that disrupts ER to Golgi trafficking of Kv3.1 channels, affecting neuronal excitability.

The paper identifies small molecule modulators of TMC1 channels using structure-based screening and validates their effects on dye uptake in cochlear explants.

This study identifies a unique sodium permeability in the C. elegans K2P channel UNC-58, driven by an atypical cysteine residue in its selectivity filter, highlighting the need for functional experiments to understand sequence variations in potassium channels.