David Ramírez

The paper identifies small molecule modulators of TMC1 channels using structure-based screening and validates their effects on dye uptake in cochlear explants.

This study investigates how GLP-1R signaling shapes β-cell heterogeneity by analyzing calcium dynamics in islets from different mouse models and humanized KO mice.

This study shows that PIP2-Tmie interactions, not myosin motors, drive slow adaptation in mammalian hair cells, as demonstrated by rescue experiments and disruption studies.

This study identifies a unique sodium permeability in the C. elegans K2P channel UNC-58, driven by an atypical cysteine residue in its selectivity filter, highlighting the need for functional experiments to understand sequence variations in potassium channels.

The paper investigates how two plant glucosinolate transporters (GTRs) recognize and transport different substrates by mutating residues and analyzing their effects on substrate preference.