David C. Hay

This study generates hepatocyte-like cells from sheep embryonic stem cells using a serum-free method, showing hepatic functions and gene expression patterns.

ProteinFlux predicts protein conformational dynamics influenced by post-translational modifications using a generative framework, outperforming traditional methods in speed and accuracy.

This study identifies PTPRK's role in promoting hepatocyte metabolic reprogramming in obesity by regulating glycolysis and lipogenesis, with potential therapeutic implications for obesity-related liver diseases.

The paper investigates how protein aggregates are cleared during cell division, finding that ER reorganization and BiP-mediated clearance occur during mitosis and cytokinesis.