Daniel F. Q. Smith

This study shows antigen stimulation can reactivate HIV-1 proviruses integrated in repressive chromatin, suggesting deeper latency may contribute to viral rebound.

The paper presents a generative AI pipeline for discovering antifungal peptides, identifying five with activity against fungal pathogens and low cytotoxicity.

This study shows dietary L-DOPA increases melanization, immunity, and reduces lifespan in Anopheles mosquitoes, while lowering malaria parasite burden.

This study uses timelapse imaging to analyze Cryptococcus neoformans infection dynamics in Galleria mellonella, revealing two distinct mortality phases and deterministic infection progression.

This study shows that peroxisomes in Cryptococcus neoformans regulate virulence and cell density sensing through metabolic pathways and mitochondrial retrograde signaling.

The paper collects and analyzes fungal isolates from urban neighborhoods in Baltimore, finding that warmer area isolates show greater thermotolerance and lighter pigmentation, suggesting local adaptation to heat.

This study shows that glutathione metabolism in Cryptococcus neoformans affects virulence by modulating redox processes and melanin production in a murine infection model.

The paper shows that environmental Cryptococcus neoformans strains undergo genomic and phenotypic changes during mammalian infection, suggesting animal virulence drives genetic adaptation.