Stephanie L. Grella

This study shows that reactivating specific cocaine-associated memories in the dorsal dentate gyrus can reduce cocaine-induced reinstatement of drug-seeking behavior, with effects varying by the stage of drug exposure.

This study shows that ventrolateral orbitofrontal cortex activity is required for updating spatial memories when new information is present, as evidenced by behavioral and hippocampal ensemble impairments.

The paper shows that reactivating positive memories during fear memory recall reduces conditioned fear in mice, suggesting a method to disrupt negative affective states through memory updating.

The paper identifies distinct cell populations in the ventral hippocampus that encode appetitive and aversive memories, showing molecular, cellular, and projection-specific differences.

This study shows that optogenetic reactivation of fear engrams in ethanol-exposed mice reduces fear responses, mimicking extinction, despite impaired extinction learning.

This study shows chronic optogenetic stimulation of hippocampal engrams in male mice enhances specific social behaviors but not others, with no detectable changes in neural activity markers.

This study shows that odor can delay the de-contextualization of fear memories, maintaining hippocampal dependence even at remote time points.