Author
Harvard UniversityORCID 0000-0002-7913-2641Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Robert J. Fisher, Kihyun Park, Kwangwoon Lee…·Rhoda M. Alani
The paper shows that inhibiting the CoREST complex with corin alters RNA splicing, increases neoantigen expression, and enhances tumor immunity in melanoma.
Payal Tiwari, Kayla J. Colvin, Sarah Y. Kim…·Robert T. Manguso
The paper identifies CREB5 as a driver of immunotherapy resistance in melanoma by promoting collagen matrix deposition, which activates LAIR1 signaling on immune cells.
Hülya F. Taner, Wang Gong, Zackary R. Fitzsimonds…·Yu L. Lei
This study identifies a SOX2-CCL2-IL1 pathway that drives immune suppression in precancerous epithelial dysplasia, promoting malignant transformation.
Satoru Morita, Tomofumi Ando, Hiroto Kikuchi…·Dan Gabriel Duda
Liver fibrosis limits the survival benefit of multikinase inhibitor immunotherapy in hepatocellular carcinoma by promoting innate immune-mediated hepatotoxicity despite preserved tumor control.
Charles S. Comiter, Xingjian Chen, Eeshit Dhaval Vaishnav…·Aviv Regev
SCHAF generates spatially resolved single-cell transcriptomes from H&E histology images using vision transformers and adversarial learning, showing good agreement with ground-truth data.