Author

Basel A. Karim

Stanford UniversityORCID 0000-0002-7928-0433Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1

Frequent Co-Authors

Nathanael S. GrayiD· 2 shared Roman C. SarottiD· 2 shared Sai P. GourisankariD· 2 shared A. KrokhotiniD· 1 shared Brendan G. DwyeriD· 1 shared Briana Howard· 1 shared Gabriela AlexeiD· 1 shared Gerald R. CrabtreeiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

Nathanael S. GrayORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMar 14, 2025

Rewiring the fusion oncoprotein EWS/FLI1 in Ewing sarcoma with bivalent small molecules

Michael J. Bond, Ryan P. Golden, Giulia DiGiovanni…·Kimberly Stegmaier

This study develops a bivalent small molecule, EB-TCIP, that relocalizes EWS/FLI1 to induce BCL6 target genes, demonstrating a strategy to target fusion oncoproteins in Ewing sarcoma.

1 citation

humanChIP-seq

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Cancer BiologySciencePeer-reviewedOct 3, 2024

Borrowing Transcriptional Kinases to Activate Apoptosis

Roman C. Sarott, Sai P. Gourisankar, Basel A. Karim…·Nathanael S. Gray

The paper develops bivalent molecules that convert kinase inhibitors into activators of proapoptotic genes, achieving selective killing of DLBCL cells with low cytotoxicity.

83 citationstop 1%

humanproteomics

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