Author

Wei Xiong

Brown Foundation Institute of Molecular Medicine for the Prevention of Human DiseasesORCID 0000-0002-8087-5047Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:biophysical modeling· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Fransisca LeonardiD· 2 shared Han Nhat Tran· 2 shared Jia-Shiun LeuiD· 2 shared Kyuson YuniD· 2 shared Ningyan ZhangiD· 2 shared Nourhan H AbdelfattahiD· 2 shared Reece Kang· 2 shared Zhiqiang AniD· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Fransisca LeonardORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintNov 12, 2026

S100A4 Is a Targetable Regulator of Immune Suppression in Glioblastoma

Thomas Wong, Jia-Shiun Leu, Maryam Faisal…·Kyuson Yun

This study identifies S100A4 as a targetable regulator of immune suppression in glioblastoma, showing its inhibition enhances immunotherapy response and survival.

DOI 10.64898/2026.11.10.765528

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologyCancer LettersPeer-reviewedApr 8, 2026

Combined inhibition of S100A4 and TIGIT suppresses late-stage breast cancer metastasis to the lung by activating T and NK cells

Jia-Shiun Leu, Hui Deng, Han Nhat Tran…·Kyuson Yun

This study shows that combining S100A4 and TIGIT inhibition suppresses breast cancer lung metastasis by enhancing T and NK cell activity in late-stage disease.

2 citations

mousebulk RNA-seq

𝕏 PostBluesky