J. Simon C. Arthur

The paper investigates the role of MKK3 in adipose tissue during obesity, finding that its activation protects against insulin resistance by enhancing p38-beta signaling.

The paper identifies MSK1's role in TRPV1 upregulation in specific nociceptors, linking it to inflammatory pain and heat hyperalgesia.

This study compares IL-33-induced proteomic responses across different mast cell types and identifies p38 MAPK as a key regulator of the inflammatory programme.

This study shows that C. albicans infection suppresses BMDM immune responses to LPS or P. aeruginosa, including cytokine production, suggesting a mechanism for immune evasion.

This study shows that LPS induces metabolic changes in B cells, including amino acid uptake and cholesterol metabolism, which are essential for proliferation.

The paper optimizes Spectronaut search parameters to reduce false positives in DIA proteomics with minimal loss of true positives in heterogeneous samples.

The paper uses quantitative proteomics to identify tissue-specific, infection-induced, and species-specific neutrophil protein signatures in mice and humans.

The paper shows that MSK-mediated phosphorylation of histone H3 at serine 28 couples MAPK signaling with chromatin remodelling and immediate early gene expression to induce pro-hypertrophic cardiac transcriptional responses.