Robert Sellers

PISTACHIO improves spatial cell-type deconvolution in tumours using proteomics constraints and non-negative matrix factorization.

This study evaluates DLMDA for improving DNA yield from FFPE samples but finds it reduces CNA sensitivity.

This study identifies IRF2BP2 as a critical regulator of transposable element silencing in AML, showing its loss leads to TE activation and leukemia cell death.

The paper compares organotypic cultures and xenografts of a human lung squamous cell carcinoma model, finding that xenografts better reflect tumor gene expression and reveal NOTCH1 loss as a driver.

This study shows glucocorticoids enhance anti-tumor immunity by inhibiting the GARP/TGF-β axis in melanoma, improving prognosis and response to immunotherapy.

The paper develops an in vitro model of lung squamous cell carcinoma using primary human bronchial epithelial cells to study genotype-phenotype relationships in cancer progression.

This study identifies granulocyte-derived resistin as a key factor in CMML that inhibits monocyte maturation and promotes immune suppression.