Meenakshi Rao

This study shows that blocking the Neurokinin 1 receptor with antagonists improves survival in C. difficile infection patients and reduces vascular inflammation.

This study identifies EGFR inhibitors as inducers of enteroendocrine cell differentiation, linking their use to treatment-associated diarrhea through STAT1 signaling activation.

This study identifies neurotensin-expressing neurons in the parabrachial nucleus that modulate colonic sensitivity and pain in colitis, suggesting neurotensin as a therapeutic target.

This study identifies IBD type-associated EGC activation signatures and reveals TNF/IFN-γ-driven necroptosis of activated enteric glia in inflammatory bowel diseases.

This study shows that redox balance, regulated by NOX1 and HIF1-IDH1 interactions, controls epithelial stem cell fate in the distal colon niche.

This study shows that enteric glia regulate Paneth cell secretion and microbial ecology but have minimal effects on overall intestinal epithelial transcription.

This study shows androgens regulate colonic motility in mice and humans, with lower testosterone levels linked to IBS symptom severity.

This study shows gut-innervating nociceptors protect against Salmonella typhimurium infection by modulating microbiota and Peyer’s patch microfold cells.