Author

Mariana T. Ruckert

Universidade de São PauloORCID 0000-0002-8282-4454Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Costas Andreas LyssiotisiD· 2 shared Abhijit ParoliaiD· 1 shared Andrew D. PattersoniD· 1 shared Austin E. EadesiD· 1 shared Bailey A. ByeiD· 1 shared Benjamin S. HalliganiD· 1 shared Brandon CheniD· 1 shared David A. HannaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCell Biology

Costas Andreas LyssiotisORCID

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2 papers

Recent·Most cited

Cell BiologyMolecular CellPeer-reviewedFeb 13, 2026

BRD4-mediated epigenetic regulation of endoplasmic reticulum-mitochondria contact sites is governed by the mitochondrial complex III

Brandon Chen, Drew C. Stark, Pankaj Vilas Jadhav…·Yatrik Madhukar Shah

The paper identifies fedratinib as a drug that increases endoplasmic reticulum-mitochondria contact sites by inhibiting BRD4, revealing a novel epigenetic pathway linking ERMCS to cellular metabolism.

8 citations

humanexperimental assay

𝕏 PostBluesky

Cancer BiologyScientific ReportsPeer-reviewedSep 30, 2025

DUSP6 is upregulated in metastasis and influences migration and metabolism in pancreatic cancer cells

Mariana T. Ruckert, R. McKinnon Walsh, Bailey A. Bye…·Vanessa S. Silveira

This study shows DUSP6 is upregulated in pancreatic cancer metastasis and independently influences cell migration and metabolism, suggesting it as a therapeutic target.

4 citations

humanbulk RNA-seq

𝕏 PostBluesky