Todd L. Lowary

Converting human antibody A194-01 from IgG1 to IgM broadens glycan recognition and boosts urinary lipoarabinomannan detection, and RU95-C1, a mannan-targeting antibody, works as a capture partner.

The paper evaluates how glycan-binding proteins and immune cells recognize mirror-image glycans, finding widespread binding and donor-specific recognition of L-glycans.

The paper identifies a type VII-secreted toxin in mycobacteria that enables inter-bacterial competition by targeting arabinogalactan.

The paper identifies nocardial cell wall arabinogalactan as the cause of Fungitell(R) cross-reactivity in nocardiosis and shows that {beta}-glucose substitution in the galactan domain is responsible.

This paper evaluates the multiplexed liquid glycan array (LiGA) for detecting ABO blood group antibodies in human serum, identifying its strengths and limitations.

This study identifies the Pel polysaccharide as a driver of autoaggregation in S. intermedius, linking it to biofilm formation and increased pathogenicity.

This study presents cryo-EM structures of AftB from Mycobacterium chubuense, revealing its architecture and mechanism for terminal arabinosylation in mycobacterial cell wall biosynthesis.

This study determines the cryo-EM structures of PimE from Mycobacterium abscessus and elucidates its mechanism of action, providing insights for anti-TB drug development.