Author
Zelin Chen
Chinese Academy of SciencesORCID 0000-0002-8376-7367Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2017-2022 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 21 mutual co-author links5 papers
Recent·Most cited
- Developmental BiologyNature GeneticsPeer-reviewed
Integrated annotation and analysis of genomic features reveal new types of functional elements and large-scale epigenetic phenomena in the developing zebrafish
Damir Baranas̆ić, Matthias Hörtenhuber, Piotr J. Balwierz…·Ferenc Müller
The paper creates a central repository for zebrafish developmental genomics data, identifies new cis-regulatory elements, and compares regulatory elements between zebrafish and mouse.
101 citationstop 2% - Geneticsnpj Regenerative MedicinePeer-reviewed
A subset of SMN complex members have a specific role in tissue regeneration via ERBB pathway-mediated proliferation
Wuhong Pei, Lisha Xu, Zelin Chen…·Shawn Michael Burgess
The paper identifies gemin3 as a regeneration-essential gene in zebrafish and shows smn1, gemin3, and gemin5 inhibit the ErbB pathway to promote cell proliferation during tissue regeneration.
21 citations - GenomicsScience AdvancesPeer-reviewed
De Novo assembly of the goldfish (Carassius auratus) genome and the evolution of genes after whole genome duplication
Zelin Chen, Yoshihiro Omori, Sergey Koren…·Shawn Michael Burgess
This paper presents a high-quality goldfish genome assembly and analyzes gene evolution after whole genome duplication, identifying gene divergence patterns across tissues.
- GeneticsG3 Genes Genomes GeneticsPeer-reviewed
Highly-efficient Cpf1-mediated gene targeting in mice following high concentration pronuclear injection
Dawn E. Watkins‐Chow, Gaurav K. Varshney, Lisa J Garrett…·Shawn Michael Burgess
This study shows that Cpf1 can achieve high gene targeting rates in mice, sometimes surpassing Cas9, but requires higher mRNA and guide concentrations.
27 citations